Metformin Side effects. Tips to Avoid

Metformin side-effects | Metformin adverse effects | How to avoid metformin side effects




Many people with type 2 diabetes are administered metformin, which is also occasionally used to treat polycystic ovarian syndrome (PCOS) and other disorders. Despite the fact that the medicine is generally well-tolerated and regarded as safe, some side effects may occur. In this blog post, we'll talk about some of the metformin side effects that are most frequently experienced and offer advice on how to prevent or lessen them.

Gastrointestinal distress

Gastrointestinal distress, which includes nausea, upset stomach, diarrhea, and abdominal pain, is the most typical side effect of metformin. When someone initially begins taking the medicine, these adverse effects are typically more frequent, but they usually subside with time. These symptoms, nevertheless, can occasionally be persistent and seriously impair a person's quality of life. It is advised to take metformin with meals in order to prevent or lessen the severity of these adverse effects. This can lessen the probability of stomach upset and assist to slow down the absorption of the drug. The severity of gastrointestinal side effects can also be lessened by starting with a low dose of the medicine and gradually increasing it over time.

Lactic acidosis

Lactic acidosis, a disease marked by elevated amounts of lactic acid in the blood, is another side effect connected to metformin. If untreated, lactic acidosis is a dangerous condition that can be fatal. People with particular illnesses, such as renal or liver disease, or those who are dehydrated, are more likely to develop lactic acidosis. If you have any of these underlying illnesses, it's crucial to let your doctor know before starting metformin in order to lower the risk of lactic acidosis. It's crucial to drink enough of water in order to stay hydrated.

Lack of vitamin B12

A third side effect of metformin is a lack of vitamin B12 because metformin prevents the body from absorbing vitamin B12. Anemia, nerve damage, and cognitive decline may result from this. It is advised that people on metformin frequently take a vitamin B12 supplement or eat foods high in vitamin B12, such as dairy products, eggs, and meat, to prevent vitamin B12 insufficiency.

Hypoglycemia (low blood sugar)

Despite being a rare adverse effect, hypoglycemia (low blood sugar) can also be brought on by metformin. As a result, those who take it should constantly check their blood sugar levels to make sure that this does not happen. For those who also take sulfonylureas or insulin, two diabetic medications that can also lower blood sugar levels, or other diabetes medications like those, this is very crucial. Regular blood sugar monitoring and dosage adjustments of metformin or other drugs are necessary to prevent hypoglycemia.

Last but not least, it's crucial to remember that metformin may have different side effects on various populations, such as the elderly or those who have heart or lung diseases. It's crucial to speak with a healthcare professional to determine whether it is safe to use Metformin and to adjust dosages accordingly.

Sulfonylureas 

Sulfonylureas are a group of medicines used to treat type 2 diabetes.

Some commonly prescribed Sulfonylureas include:
  • DiaBeta, Glynase, or Micronase (glyburide or glibenclamide)
  • Amaryl (glimepiride)
  • Diabinese (chlorpropamide)
  • Glucotrol (glipizide)
  • Tolinase (tolazamide)
  • Tolbutamide.

Other signs & symptoms:

  • Weakness
  • Tiredness
  • nausea
  • Vomiting
  • Stomach pain
  • Dizziness
  • Lightheadedness
  • Headache
  • Irritability
  • Excessive hunger
  • Excess sweating
  • Tachycardia
  • Abnormally fast or slow heartbeat

Be aware of the adverse effects

For many individuals with type 2 diabetes, metformin is a safe and effective drug, but it's vital to be aware of the adverse effects that could occur and to take precautions to prevent or lessen them. 

Metformin users can lessen the frequency and severity of gastrointestinal side effects by taking the medicine with meals, starting with a low dose, and gradually increasing the dose over time. 

Additionally, people taking metformin can lessen their chance of developing lactic acidosis by drinking enough of water and telling their doctor about any underlying illnesses. 

Consuming vitamin B12-rich foods or supplements can check blood levels and prevent deficiencies.


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